A 15-year-old girl is incarcerated in a Chicago mental hospital in 1981 and kept there for three years because she won't wear a dress. A Winn-Dixie truck driver is fired from a job he held for twenty years when his boss learns that he wears women's clothes at home. A small-time hustler in Falls City, Nebraska, is raped and then murdered when he's discovered to be physically female. A woman bleeds to death after a Washington, DC, hit-and-run accident when, after finding male genitals under her clothes, paramedics stand by laughing.

M or F? For most of us that's a simple question, decided while we were in utero. Checking off that box--at the doctor's, on the census, on a driver's license--takes scarcely a thought. But there's an emerging movement of increasingly vocal people whose bodies or behavior unsettle that clear division. They're calling themselves "transgendered": It's a spongy neologism that, at its broadest, absorbs everyone from medically reassigned transsexuals to cross-dressing men to women so masculine that security guards are called to eject them from women's restrooms. Fellow travelers include intersexuals (once called hermaphrodites), whose bodies are both/and rather than either/or. The slash between M/F cuts painfully through these lives.

And so they've started to organize. Brought together by the Internet, inspired by the successes of the gay rights movement, and with national sympathy gained from the movie Boys Don't Cry, intersex and transgender activists are starting to get a hearing in organizations ranging from college campuses to city councils, from lesbian and gay rights groups to pediatric conferences. And, like the feminist and gay rights movements before them, the new sex-and-gender activists may force us to rethink, in life and in law, how we define and interpret the basics of sex.

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